5 Bedroom Beach Vacation Rentals in Ocean Isle, NC

Ideal for family reunions, getaways with friends, special events, or even corporate retreats, our five-bedroom beach vacation rentals in NC provide all of the comfort and luxury you could ask for during your stay. Take a look through our immense selection of Ocean Isle Beach five-bedroom North Carolina beach homes down below! Able to sleep up to 20, our 5-bedroom beach vacation rentals allow you to make the most of your Ocean Isle Beach retreat. Prepare breakfast in the fully-equipped kitchen, take advantage of the spacious living room to socialize and bond and catch a good night’s sleep in our super-comfy beds. Since our beach vacation rentals in NC have all the comforts of home, you won’t lack anything!

Five-Bedroom Beach Vacation Rentals in NC with Lavish Amenities

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The interiors of our five-bedroom oceanfront beach rentals in North Carolina exemplify everything that makes a vacation in Ocean Isle Beach so wonderful. From serene shades mixed with bright, cheerful pops of color, to classic nautical décor interspersed with cozy touches, these details represent the relaxed vibe and high-quality comfort that make our beach vacation rentals NC perfect for your stay.

After seeing the sights around town, such as Ocean Isle Beach itself, Shallotte River Swamp Park, the Museum of Coastal Carolina, and Sunset Beach Fishing Pier, you can return to the comfort of our five-bedroom North Carolina beach homes

Enjoy downtime entertainment and relaxation in the form of a movie night with your guests using the flat screen in the wide-open living room, or simply enjoy the company and conversation of your guests on the plush furnishings. Or, if you’re not quite done with the beach, you can head to the sands just steps away from many of our Oceanfront five-bedroom beach rentals in North Carolina.

Full-sized kitchens equipped with generous countertops and high-end appliances allow you to make vacation memories and save money at the same time by preparing a feast for your guests.

You can impress them with your culinary prowess, then enjoy your flavorful meal at the dining table, bar seating, or out on the deck or balcony of these five-bedroom beach rentals in Ocean Isle, NC for a breezy seaside al fresco experience. Alternatively, you can head outside and wind down after dinner, taking in the sunset and ocean views.

As the day draws to a close, you can treat yourself to a luxurious bath or a hot shower in the immaculate, resort-quality restrooms within these homes. Then, after you’ve washed up and you’re feeling at your peak vacation relaxation, you can slide into the soft linens of your comfy bed. When you wake, you’ll find that the next day will be better than your sweetest dreams!

Activities and Attractions in Ocean Isle Beach

In and around Ocean Isle Beach, you'll find sightseeing and recreation ranging from historic war sites to eight miles of breathtakingly immaculate beaches.

Plan your beach days around swimming, boating, kayaking, canoeing, and stand-up paddleboarding in the Atlantic Ocean's glistening waves, enjoying the warm waters and idyllic atmosphere. Ocean Isle Beach's water stays an average of ten degrees warmer than those of the Outer Banks.

There are other natural sights you'll want to see near our beach vacation rentals in NC, such as the annual summer hatching season of the indigenous loggerhead turtles. As their babies emerge from their shells, they race to the ocean in a bid for survival. Additionally, the neighboring town of Sunset Beach is home to five of locales on the North Carolina Birding Trail, making it an excellent place to catch a glimpse of native and migrating bird species.

You and your guests can also see the incredible swamp ecosystem just outside of Ocean Isle Beach at Shallotte River Swamp Park. Here, they offer scenic airboat eco-tours of the diverse swamplands, as well as zipline tours and an exciting aerial adventure park with obstacles.

The Museum of Coastal Carolina is another great place to learn about Ocean Isle Beach's spectacular natural environment. Between its exhibits and live showings of turtle hatchings and tank cleanings, your guests will be fascinated by the natural beauty of Ocean Isle Beach.

Similarly, Ingram Planetarium in Sunset Beach is also a sight to behold. Their live star shows, set to lasers and the music of legendary bands like The Beatles and Pink Floyd, add a dimension of family-friendly magic and wonder to your nights in Ocean Isle Beach.

Just a short drive away from our five-bedroom beach rentals in Ocean Isle, NC, you can visit incredible places like Wilmington, Myrtle Beach, the Fort Fisher Civil War Museum, the USS North Carolina Battleship Memorial, and Fort Anderson. Myrtle Beach offers the excitement of the big city and Spring Break scene, while Wilmington and the various historic sites mentioned all showcase the critical role that our region has had in three major wars: the Revolutionary War, the Civil War, and World War II.

In between your outings, you can refuel with a delicious meal from restaurants like Antonio's, La Cucina, Sugar Shack, Ocean Isle Fish Company, and Sharky's. Then, pick up a souvenir from one of the great local shops around town, or stop in for dessert at Sunset Slush or Breakers.

Experience One of Our Beach Vacation Rentals in NC For Yourself!

Contact our reservation specialists today for specifics on the attractions and activities you’ll encounter in Ocean Isle Beach when you book your accommodations in one of our extraordinary five-bedroom beach vacation rentals in NC!

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This is a VayKLife participating property! Receive a $245 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 11 Duneside Drive This mid-island home offers 5 bedrooms and 4 bathrooms. Enjoy features such as ... Read more »

27 people are interested in this property!

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  • Location: Mid-Island
  • Property Type: House
  • Sleeps: 11 Bedrooms: 5
  • Beds: 4Q, 3S
  • Baths: 4
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $2,365.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 124 Shallotte Boulevard  5 bedrooms and 4 full & 2 half bathrooms. Enjoy features such as central... Read more »

18 people are interested in this property!

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  • Location: Mid-Island
  • Property Type: House
  • Sleeps: 13 Bedrooms: 5
  • Beds: 2K, 2Q, 2D, QSS, SSS
  • Baths: 4 Half: 2
  • Pets: No
  • Pool: Private Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $5,870.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 126 West First Street. This second row house offers 5 bedrooms and 5 bathrooms. Enjoy features su... Read more »

76 people are interested in this property!

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  • Location: Second Row
  • Property Type: House
  • Sleeps: 18 Bedrooms: 5
  • Beds: K, 2Q, 6D
  • Baths: 5
  • Pets: No
  • Pool: Community Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $4,640.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 13 Leland Street This charming home is a multi-level 5 bedroom, 5 bath home located on a concrete ... Read more »

23 people are interested in this property!

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  • Location: Canal
  • Property Type: House
  • Sleeps: 16 Bedrooms: 5
  • Beds: K, 8Q
  • Baths: 5
  • Pets: No
  • Pool: Private Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $5,970.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 20 Leland Street This large canal home offers 5 bedrooms and 4 bathrooms. Enjoy features such as ... Read more »

32 people are interested in this property!

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  • Location: Canal
  • Property Type: House
  • Sleeps: 14 Bedrooms: 5
  • Beds: K, 4Q, 2 Bunks
  • Baths: 4
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $3,030.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 217 East First Street 5 Bedroom Ocean View Home with canal lot and dock for boating, fishing, and... Read more »

18 people are interested in this property!

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  • Location: Second Row
  • Property Type: House
  • Sleeps: 16 Bedrooms: 5
  • Beds: K, Q, Q, Q&D, D&bunks, 2QSS
  • Baths: 5 Half: 1
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $4,375.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 24 Private Drive  OFF SEASON SPECIAL!! STAY 3 NIGHTS, GET 4TH NIGHT FREE!! Excludes holidays.  P... Read more »

28 people are interested in this property!

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  • Location: Summerplace
  • Property Type: House
  • Sleeps: 16 Bedrooms: 5
  • Beds: K, 3Q, D, 5S
  • Baths: 4 Half: 1
  • Pets: Yes
  • Pool: Private Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $5,535.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 259 West First Street This oceanfront house offers 5 bedrooms and 4.5 baths. Enjoy features such... Read more »

13 people are interested in this property!

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  • Location: Oceanfront
  • Property Type: House
  • Sleeps: 14 Bedrooms: 5
  • Beds: K, Q, Q & S, Q&S, 2D
  • Baths: 4 Half: 1
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $6,235.00

26 Raeford Street NEW FOR 2023 TIKI BAR ON GROUND LEVEL.  This canal home offers 5 bedrooms and 4 1/2 bathrooms. Enjoy features such as central heat air, microwave, dishwasher, Keurig coffee maker, standard coffee maker, washer/dryer, 6 flat screen TVs (in living room and in all 5 bedrooms), ... Read more »

21 people are interested in this property!

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  • Location: Canal
  • Property Type: House
  • Sleeps: 14 Bedrooms: 5
  • Beds: 2K, 2Q, D, 2S, DSS
  • Baths: 4 Half: 1
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $3,485.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 279 East First Street This second row home offers 5 bedrooms plus a left and 4 bathrooms. Enjoy f... Read more »

11 people are interested in this property!

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  • Location: Second Row
  • Property Type: House
  • Sleeps: 18 Bedrooms: 5
  • Beds: 5Q, 3S, 2 bunks
  • Baths: 4
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $3,845.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 374 East Second Street  This third row home offers 5 bedrooms and 4.5 bathrooms. Enjoy a reversed... Read more »

24 people are interested in this property!

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  • Location: Third Row
  • Property Type: House
  • Sleeps: 16 Bedrooms: 5
  • Beds: 3K, 4 D/D Bunks, QSS
  • Baths: 4 Half: 1
  • Pets: No
  • Pool: Private Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $4,725.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 3 Barnacle Court This Island Park home offers seclusion on a quiet street with views of the Intrac... Read more »

22 people are interested in this property!

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  • Location: Island Park
  • Property Type: House
  • Sleeps: 10 Bedrooms: 5
  • Baths: 3 Half: 1
  • Pets: No
  • Pool: Community Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $4,240.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 3 Private Drive This home in the community of Summer Place offers 5 bedrooms and 5 bathrooms. Enj... Read more »

12 people are interested in this property!

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  • Location: Summerplace
  • Property Type: House
  • Sleeps: 12 Bedrooms: 5
  • Beds: 2K, 2Q, 2D
  • Baths: 5
  • Pets: No
  • Pool: Community Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $3,195.00

425 East Third Street This east end property has a reversed floor plan with the kitchen and living area on the top floor and offers 5 bedrooms and 5.5 bathrooms. Enjoy features such as central heat and air, microwave, dishwasher, washer/dryer, 7 TVs with Roku, DVD player, internet, ceiling fans, c... Read more »

9 people are interested in this property!

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  • Location: Second Row
  • Property Type: House
  • Sleeps: 16 Bedrooms: 5
  • Beds: 7Q, 1 Bunk set
  • Baths: 5 Half: 1
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $5,065.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 42 Leland Street  This large canal home offers 5 bedrooms and 5 bathrooms. Enjoy features such as... Read more »

11 people are interested in this property!

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  • Location: Canal
  • Property Type: House
  • Sleeps: 12 Bedrooms: 5
  • Beds: 5Q, 2S
  • Baths: 5
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $5,345.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 44 Leland Street This large canal home offers 5 bedrooms and 4 bathrooms. Enjoy features such as ... Read more »

13 people are interested in this property!

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  • Location: Canal
  • Property Type: House
  • Sleeps: 18 Bedrooms: 5
  • Beds: 5Q, 4D, Futon
  • Baths: 4
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $2,965.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 47 Union Street  This newly renovated house on a concrete canal offers 5 bedrooms, 3 bathrooms, a... Read more »

26 people are interested in this property!

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  • Location: Canal
  • Property Type: House
  • Sleeps: 11 Bedrooms: 5
  • Beds: 1K, 5Q, 1QSS
  • Baths: 3
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $2,800.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 54 East First Street East side of a duplex: 5 bedrooms (King, 1 Queen & 1 Double, 2 Doubles, 2 Do... Read more »

13 people are interested in this property!

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  • Location: Oceanfront
  • Property Type: House
  • Sleeps: 20 Bedrooms: 5
  • Beds: K, Q, 7D, S/trundle
  • Baths: 4 Half: 1
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $4,040.00

This is a VayKLife participating property! Receive a $315 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 54 East First Street -W  This oceanfront duplex offers 5 bedrooms and 4.5 bathrooms. Enjoy featur... Read more »

10 people are interested in this property!

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  • Location: Oceanfront
  • Property Type: House
  • Sleeps: 20 Bedrooms: 5
  • Beds: K, 2Q, 6D, S/trundle
  • Baths: 4 Half: 1
  • Pets: No
  • Pool: No Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $4,030.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 7 Private Drive This large home in Summer Place offers 5 bedrooms and 5.5 bathrooms. Enjoy featur... Read more »

10 people are interested in this property!

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  • Location: Summerplace
  • Property Type: House
  • Sleeps: 16 Bedrooms: 5
  • Beds: 2K, 1Q, 4D, QSS
  • Baths: 5 Half: 1
  • Pets: No
  • Pool: Community Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $5,005.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 93 West First Street -Unit C This section of the oceanfront triplex offers 5 bedrooms plus small ... Read more »

14 people are interested in this property!

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  • Location: Oceanfront
  • Property Type: Triplex
  • Sleeps: 20 Bedrooms: 5
  • Beds: K, 8Q, D/S bunk
  • Baths: 5
  • Pets: No
  • Pool: For triplex Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $8,205.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 93 West First Street -Unit D This section of the oceanfront triplex offers 5 bedrooms plus small ... Read more »

17 people are interested in this property!

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  • Location: Oceanfront
  • Property Type: Triplex
  • Sleeps: 20 Bedrooms: 5
  • Beds: K, 8Q, D/S bunk
  • Baths: 5
  • Pets: No
  • Pool: For triplex Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $8,205.00

This is a VayKLife participating property! Receive a $385 credit towards vacation gear rental with qualifying reservation! 7 - 21 nights between 4/1/2024-10/31/2024 booked on or after 11/6/2023. 93 West First Street - Unit E This section of the oceanfront triplex offers 5 bedrooms plus small... Read more »

14 people are interested in this property!

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  • Location: Oceanfront
  • Property Type: Triplex
  • Sleeps: 20 Bedrooms: 5
  • Beds: K, 8Q, D/S bunk
  • Baths: 5
  • Pets: No
  • Pool: For triplex Internet: Yes
  • Smoking Allowed: No
  • Summer Rate: $8,205.00